Carglumic Acid

Carglumic acid

Carglumic acid is an analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency.

Systematic name

(2S)-2-(carbamoylamino)pentanedioic acid

Brand name(s)


Therapeutic category


Available formulations



USDMF Exclusive for US market


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