Glycerol Phenylbutyrate

 Glycerol Phenylbutyrate

 Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. Glycerol phenylbutyrate is a nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions.

Systematic name

1,3-bis[(4-phenylbutanoyl)oxy]propan-2-yl 4-phenylbutanoate

Brand name(s)

Ravicti

Therapeutic category

Hyperammonemia

Available formulations

Liquid

Approvals

USDMF Exclusive for US market

EU-WC

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