Nitrofurantoin Monohydrate

Nitrofurantoin Monohydrate

Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.8,9,10 Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts on many targets at once.Nitrofurantoin is an antibiotic used to treat urinary tract infections.

Systematic name

1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione

Brand name(s)

uradantin, Macrobid, Macrodantin

Therapeutic category

Anti-infective

Available formulations

Solid

Approvals

DMF Ready

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