Trientine Tetrahydrochloride

Trientine Tetrahydrochloride

Trientine tetrahydrochloride (brand name Cuprior) was approved for medical use in the European Union in September 2017. It is indicated for the treatment of Wilson’s disease in adults, adolescents and children five years of age or older who are intolerant to D-penicillamine therapy.

Systematic name

N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine;tetrahydrochloride

Brand name(s)

 Cuvrior

Therapeutic Category

 Treatment of Wilson's disease excluding patients intolerant to penicillamine

Suitable Formulations

Solid

Approvals

USDMF Exclusive for US market

EU-WC

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